Oh man, this was a really awesome animation! I love how culturally-fueled it is, kind of like Warlord-of-Noodles' "No Evil" series. The characters themselves are pretty likable, but also remind me of other characters; e.g., Iztlacoliuhqui -- despite the weird obsession with the little girl -- is similar to Aku from Samurai Jack, and Chicahualizteotl reminds me of Amaterasu from Okami. However, that's my own view, so it's probably not really a problem on your end. Besides, its interesting that the god in the poncho is your own character (if I'm correct) versus a different god like Quetzalcoatl (though I guess that one is overdone).
The presentation is very good, withholding the black bars at the edges of the video. The background sounds and music are great (the beginning especially reminded me of Siren). The animation is stylish; the scenes focusing on Iztlacoliuhqui delivered a good blend of sinisterness and power, the scenes with Donaji and/or her mother were cute, and the appearance of Chicahualizteotl was a mixture of Aztec and anime which worked pretty well. The voices were good, too, though Donaji's voice was a bit louder/higher compared to the others. Overall, however, this was really great and I hope that in the future there is another animation along with the webcomic.
